![]() ![]() There exist a range of tools that can be used to assess cognitive status in PD. Mild cognitive impairment in PD (PD-MCI) is found in over a quarter of patients ( 2), may be present at diagnosis ( 3) and is predictive of the risk of developing dementia ( 2), an outcome that occurs in over 80% of patients ( 4). Parkinson’s disease (PD) is a common neurodegenerative condition affecting around 1.5% of people over 65 in Europe ( 1). Age appeared to be the only associated factor for lower level of cognition, suggestive of Mild cognitive impairment in PD (PD-MCI) in PD without clinical diagnosis of dementia. People aged over 71 had poorer MoCA (Beta=0.6 (95%CI 0.44, 0.82)) and an increased odds of MoCA <26 (Beta=0.29 (95%CI 0.12, 0.70)) as well as poorer scores on several MoCA sub-domains.Ĭonclusion: We present the normative data for MoCA in people with PD without clinical dementia. Age was found as the only predictor of MoCA in this sample. Results: Data from 101 people with PD without dementia were available (mean age 71 years, 66% men). The influences of age, gender, disease duration, medication load (LEDD) and mood (HADS) on cognition were examined using regression analysis. Cognitive status was assessed using MoCA at baseline in both studies. All participants were aged 18 years or over, met UK Brain Bank criteria for PD and did not have clinical dementia. Methods: We undertook a pooled secondary analysis of data from two studies (one cross-sectional design and one clinical trial) conducted in the East of England region. Background: The Montreal Cognitive Assessment (MoCA) has been recommended as a cognitive screening tool for clinical practice and research in Parkinson’s disease (PD), yet no normative data have been published for MoCA in PD without dementia. ![]()
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